We describe the recent advances in studying biological systems via multiscale simulations. Our scheme is based on a coarse-grained representation of the macromolecules and a mesoscopic description of the solvent. The dual technique handles particles, the aqueous solvent and their mutual exchange of forces resulting in a stable and accurate methodology allowing biosystems of unprecedented size to be simulated.
This article is part of the themed issue ‘Multiscale modelling at the physics–chemistry–biology interface’.
One contribution of 17 to a theme issue ‘Multiscale modelling at the physics–chemistry–biology interface’.
- Accepted August 3, 2016.
- © 2016 The Author(s)
Published by the Royal Society. All rights reserved.